DRUG-DRUG INTERACTION IN ELDERLY PATIENTS WITH DYSLIPIDEMIA DESEASE IN A BASIC HEALTH UNITY IN SANTANA OF CARIRI, CE, BRAZIL

Abstract

This study aimed to perform an analysis of drug interactions based on data from medical prescriptions for elderly patients using drugs for dyslipidemia in a basic health unit in the city of Santana do Cariri, CE.
Data collection and analysis were carried out between August and September 2018. This is a descriptive, quantitative, retrospective, and cross-sectional study. Micromedex® platform was used to identify possible drug interactions. Elderly patients with some dyslipidemia, with a minimum age of 60 and a maximum of 89 years, were selected. A total sample of 40 prescriptions was obtained, where the population was 103 prescriptions, in which 80% were female and 20% male. A total of 37 interactions was identifi ed; among them, the drug simvastatin was more frequently interacting with other drugs, the most frequent was amlodipine. These two drugs interaction is considered serious, due to the risk of myopathies and rhabdomyolysis. In view of these results, the importance of implementing a clinical pharmacy service is observed, in order to identify possible problems related to drug-drug interactions, improving the patient pharmacotherapy and quality of life, as well as minimizing the risks for their health.