PHARMACEUTICAL CARE FOR PEDIATRIC PATIENTS WITH CONGENITAL ZIKA VIRUS SYNDROME
Abstract
Congenital Zika Virus Syndrome is a significant disease that emerged in Brazil in 2015. There is no cure for this syndrome; drug treatment aims to improve patients’ quality of life. However, drug therapy using multiple drugs can lead to adverse events and drug interactions to patients’ health. The study aimed to provide pharmaceutical care to pediatric patients with Zika Virus Congenital Syndrome. The research is a longitudinal study carried out at the Physiotherapy Clinic of the State University of Paraíba (UEPB) and the Specialized Center for Rehabilitation, both located in Campina Grande – PB, eight months. There were five pediatric patients visits, one each month, using the Phamacoterapy WorKup methodology and the Micromedex® database to identify drug interactions. Twenty-three patients, 29 prescriptions, and 71 drugs belonging to 9 pharmacological classes were evaluated. Anticonvulsants were the most prescribed, as for the existing comorbidity, eight patients had two or more etiologically related diseases. In the study, there were 35 (49.2%) drug-drug interactions, of these with severe effect 8 (22.9%), moderate 23 (65.7%), minor 4 (11.4%), and none with contraindicated effect, as well as 32 drug-food interactions and 43 druglaboratory interactions. Among the problems related to medications, 42 were identified, inefficiency/ loss of effectiveness and 23 (55%) being the most frequent. Therefore, it is concluded that pharmacotherapeutic follow-up to pediatric patients with Congenital Zika Virus Syndrome is essential to assess these drugs’ rational use. Pharmaceutical Care can make a difference in the safe and proper use of drugs.
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PDF (Português (Brasil))DOI: http://dx.doi.org/10.14450/2318-9312.v33.e1.a2021.pp59-66
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Copyright (c) 2021 Beatriz Patrício Rocha, José Agnaldo Morais de Oliveira Júnior, Kallyne Medeiros, Rosemary Souza Cunha Lima, Patrícia Trindade Costa Paulo
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Infarma - Ciências Farmacêuticas
ISSN - 2318-9312 (Versão eletrônica)
ISSN - 0104-0219 (Versão impressa)
Conselho Federal de Farmácia - CFF
SHIS QI 15 Lote "L" - Lago Sul - Brasília - DF
CEP: 71635-615 - Fone: (61)3878-8751
e-mail:infarma@cff.org.br
Diretoria
Walter da Silva Jorge João, Presidente do Conselho Federal de Farmácia
Lenira da Silva Costa, Vice-Presidente do Conselho Federal de Farmácia
João Samuel de Morais Meira, Tesoureiro do Conselho Federal de Farmácia
Luiz Gustavo de Freitas Pires, Secretário-Geral do Conselho Federal de Farmácia