ANTIOXIDANT ACTIVITY OF THE AERIAL PARTS AND THE FLOWERS OF CHILIOTRICHUM DIFFUSUM (G. FORST.) KUNTZE (ASTERACEAE), A MEDICINAL PLANT USED BY THE ONAS

Sandra Marcela Alcalde Bahamonde, Carlos Alberto Taira, María Luján Flores, Osvaldo León Córdoba

Resumo


The antioxidant capacity of Chiliotrichum diffusum, a medicinal plant used in the traditional medicine of the Onas (original people of Patagonia), was studied by using the DPPH method, to explain the properties associated to the traditional use of this species. Ethyl ether (or dichloromethane from decoction of the flowers) and the ethyl acetate fraction from ethanol and aqueous extracts, showed free radical scavenging capacity on DPPH•. The results of the quantitative determination of this activity in ethyl ether and the ethyl acetate fraction from ethanol extract of aerial parts showed SC50 of 5.2 and 3.5 μg/mL, respectively. Dichloromethane and ethyl acetate fractions of the aqueous extracts from flowers showed SC50 values of 35.0 and 9.5 μg/mL. The principal flavonoids found were kaempferol, quercetin and their derivates. These results showed a relation of the phenols evidenced in the aerial parts and flowers and the antioxidant activity; also explained, at least partially, the medicinal properties described, and the use of this plant in the traditional medicine of the Onas.


Palavras-chave


Antioxidants; Asteraceae; Chiliotrichum diffusum; Onas; Patagonia

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DOI: http://dx.doi.org/10.14450/2318-9312.v31.e2.a2019.pp113-120

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Direitos autorais 2019 Osvaldo León Córdoba

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Infarma - Ciências Farmacêuticas

ISSN - 2318-9312 (Versão eletrônica)

ISSN - 0104-0219 (Versão impressa)

Conselho Federal de Farmácia - CFF

SHIS QI 15 Lote "L" - Lago Sul - Brasília - DF

CEP: 71635-615 - Fone: (61)3878-8751

e-mail:infarma@cff.org.br

Diretoria

Walter da Silva Jorge João, Presidente do Conselho Federal de Farmácia

Lenira da Silva Costa, Vice-Presidente do Conselho Federal de Farmácia

João Samuel de Morais Meira, Tesoureiro do Conselho Federal de Farmácia

Luiz Gustavo de Freitas Pires, Secretário-Geral do Conselho Federal de Farmácia