GENETIC CHANGES AND THEIR IMPLICATIONS FOR RESISTANCE TO ANESTHESIA AND THE CHOICE OF ANESTHETIC TECHNIQUE: ANALYSIS OF CLINICAL ASPECTS
Abstract
Choosing the type of anesthetic to be used in patients with genetic variations requires a detailed study of genetic changes and constant patient onitoring. Thus, it was aimed to analyze the implications that genetic changes represent in resistance to anesthetics and the choice of anesthetic techniques. A narrative review was conducted in May 2019 in the LILACS (Latin American and Caribbean Literature in Health Sciences), Medline, Scopus, Cochrane Library, and Web of Science databases. Twelve articles were selected with the following descriptors: genetics, local anesthesia; monitoring; sodium channels; neuromuscular monitoring. The literature on the genetics of resistance to anesthesia deals with genetic and clinical aspects of related diseases, demonstrating the evolution of knowledge of genetics and anesthesia, in addition to highlighting the techniques used in these cases. The evidence found described genetic and clinical information about the diseases, emphasizing the implications of late, early or unexpected effects related to anesthetic induction.
Keywords
Full Text:
PDF (Português (Brasil))DOI: http://dx.doi.org/10.14450/2318-9312.v33.e2.a2021.pp131-137
Refbacks
- There are currently no refbacks.
Copyright (c) 2021 Talita Ponte Mendes, Maria Natália Feitosa de Sousa, Franklin de Castro Alves Neto, Ivana Cristina Vieira de Lima Maia, Nely Marjollie Guanabara Teixeira Reis
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Infarma - Ciências Farmacêuticas
ISSN - 2318-9312 (Versão eletrônica)
ISSN - 0104-0219 (Versão impressa)
Conselho Federal de Farmácia - CFF
SHIS QI 15 Lote "L" - Lago Sul - Brasília - DF
CEP: 71635-615 - Fone: (61)3878-8751
e-mail:infarma@cff.org.br
Diretoria
Walter da Silva Jorge João, Presidente do Conselho Federal de Farmácia
Lenira da Silva Costa, Vice-Presidente do Conselho Federal de Farmácia
João Samuel de Morais Meira, Tesoureiro do Conselho Federal de Farmácia
Luiz Gustavo de Freitas Pires, Secretário-Geral do Conselho Federal de Farmácia