Medicinal plant versus conventional medicine interaction in arterial hypertension treatment

Authors

  • Fábia Jéssica Batista Ataliba IPOG - Instituto de Pós-Graduação e Graduação Av. Monsenhor Walfredo Leal, 503 Centro, João Pessoa - PB, 58020-540
  • Danielly Albuquerque da Costa Universidade Federal da Paraíba Centro de Ciências da Saúde Cidade Universitária, s/n Castelo Branco, João Pessoa - PB 58051-900
  • Andrezza Duarte Farias Universidade Federal de Campina Grande Centro de Educação e Saúde Sítio Olho D'água da Bica S/N Centro - Cuité - PB 58175-000
  • Júlia Beatriz Pereira Souza Universidade Federal de Campina Grande Centro de Educação e Saúde Sítio Olho D'água da Bica S/N Centro - Cuité - PB 58175-000

DOI:

https://doi.org/10.14450/2318-9312.v29.e2.a2017.pp90-99

Keywords:

phytotherapy, drug interactions, hypertension

Abstract

Hypertension, among chronic diseases, appears as health problem with one of the greatest magnitude, at present is one of the main causes of cardiovascular morbidity and mortality in Brazil. The treatment consists in the use of synthetic
drugs and medicinal plants, and this association is getting even more frequent, increasing the risks of interactions. This work is aimed to describe, through a literature review, the main interactions between herbal and synthetic drugs used in the therapy of hypertension and discuss the implications of these products concomitant use. A narrative literature review was carried out in papers published in the period 2006-2016 addressing drug interactions with medicinal plants from the ethnopharmacological survey, followed by studies of antihypertensive activity confirmation. The plants recognized for the hypertension treatment were Allium sativum, Alpinia zerumbet, Citrus sp., Lippia alba, Passiflora sp., Cymbopogon citratus, Sechium edule. Possible interactions of these plants with synthetic drugs to treat hypertension were evaluated.
It was noted that the main interactions involved in the use of herbal associated with the use of medications are a pharmacodynamic type. Thus it is necessary to be cautious when associating the use of plants with synthetic drugs.

Author Biographies

Fábia Jéssica Batista Ataliba, IPOG - Instituto de Pós-Graduação e Graduação Av. Monsenhor Walfredo Leal, 503 Centro, João Pessoa - PB, 58020-540

Farmacêutica graduada pela Universidade Federal de Campina Grande (UFCG), Cuité-PB, Brasil. Discente do Curso de Especialização em Farmácia Clínica e Atenção Farmacêutica no IPOG – João Pessoa.

Danielly Albuquerque da Costa, Universidade Federal da Paraíba Centro de Ciências da Saúde Cidade Universitária, s/n Castelo Branco, João Pessoa - PB 58051-900

Bacharelado em Farmácia/Doutorado.

Professor Adjunto do Departamento de Fisiologia e Patologia da Universidade Federal da Paraíba (UFPB), João Pessoa-PB, Brasil. Responsável pelas disciplinas de Fitoterapia e Homeopatia.

Andrezza Duarte Farias, Universidade Federal de Campina Grande Centro de Educação e Saúde Sítio Olho D'água da Bica S/N Centro - Cuité - PB 58175-000

Bacharelado em Farmácia/Mestrado.

Professor Assistente do Curso de Bacharelado em Farmácia da Universidade Federal de Campina Grande (UFCG), Cuité-PB, Brasil. Responsável pelas disciplinas de Introdução à Farmácia, Deontologia Farmacêutica e Atenção Farmacêutica.

Júlia Beatriz Pereira Souza, Universidade Federal de Campina Grande Centro de Educação e Saúde Sítio Olho D'água da Bica S/N Centro - Cuité - PB 58175-000

Professora Adjunto do Curso de Bacharelado em Farmácia do Centro de Educação e Saúde da Universidade Federal de Campina Grande, responsável pelas disciplinas de Controle de Qualidade de produtos farmacêuticos e Farmacobotânica.

 

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Published

2017-06-30

How to Cite

Ataliba, F. J. B., da Costa, D. A., Farias, A. D., & Souza, J. B. P. (2017). Medicinal plant versus conventional medicine interaction in arterial hypertension treatment. Infarma - Pharmaceutical Sciences, 29(2), 90–99. https://doi.org/10.14450/2318-9312.v29.e2.a2017.pp90-99

Issue

Vol. 29 No. 2 (2017)

Section

Review Article

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