EVALUATION OF ANTIDANDRUFF SHAMPOO QUALITY

Abstract

Superficial mycoses are fungal infections located in various parts of the body, being among the main reasons for dermatological consultations. Among the most common superficial mycoses, dandruff and seborrheic dermatitis are distinguished by their universal distribution and are frequently associated with colonization by fungi of the genus Malassezia. Shampoos containing different antifungal actives such as zinc pyrithione, ketoconazole, and cyclopirox olamine are the main treatments for such conditions. These products, because they have wide use by the population, have the necessity of proving their quality, also verifying their effectiveness, through the quality control. The present study aimed to evaluate the quality parameters of antidandruff shampoos, taking into account the requirements for products for this purpose. Analyzes of the labeled chemical composition, organoleptic, physicochemical characteristics (pH, viscosity, centrifuge test, density, foam index) and microbiological potency tests were performed, using Candida albicans and Aspergillus niger as biological markers of efficacy. After the tests carried out on five commercial samples, all were approved for organoleptic analysis and centrifugal testing. While about pH, sample 4 was out of standards. In the viscosity test, only sample 5 was performed by that described in the literature. The density values were slightly higher than those found in the literature. However, there is no influence of this parameter on the quality of the evaluated products. In the foam index, samples 1 and 2 showed higher foam consistency. After the efficacy test, only samples 1, 2 and 3 were effective in combating the test microorganisms. All samples presented antidandruff actives with proven action in the literature.