QUALITY CONTROL OF 2% KETOCONAZOLE SHAMPOOS IN COMPOUNDING PHARMACIES IN PORTO VELHO, RO, BRAZIL

Authors

  • Eva Maria Xavier Lopes Faculdades Integradas Aparício Carvalho-FIMCA. Bacharelado em Farmácia. Rua das Ararás, 241-Eldorado, CEP 78912-640. Porto Velho, RO, Brasil.
  • Fábio Lopes Moreira de Castilho Faculdades Integradas Aparício Carvalho-FIMCA. Bacharelado em Farmácia. Rua das Ararás, 241-Eldorado, CEP 78912-640. Porto Velho, RO, Brasil.
  • Victória Carolina Freire de Castro Faculdades Integradas Aparício Carvalho-FIMCA. Bacharelado em Farmácia. Rua das Ararás, 241-Eldorado, CEP 78912-640. Porto Velho, RO, Brasil.

DOI:

https://doi.org/10.14450/2318-9312.v31.e3.a2019.pp155-162

Keywords:

shampoo, quality analysis, pharmacies masterful, ketoconazole 2%

Abstract

Shampoos are products for cleaning or fixation of substances with dermatological action. Ketoconazole shampoos have the purpose of treating and preventing fungal infections caused by Malassezia globosa. Due to these are high-consumption shampoos it is necessary to confirm the quality of the products handled in the compounding pharmacies. The objective of this work was to perform quality analyzes of the ketoconazole shampoos from compounding pharmacies in Porto Velho, RO. Organoleptic analyzes, hydrogenionic potential (pH), density determination, viscosity, foaming potential, centrifugation test, and spectrophotometric assay were performed. The five samples were satisfactory for the organoleptic analysis; about pH, only sample B fit within the standards. About density, samples A and C were satisfactory. Considering viscosity, only E was unsatisfactory; and foaming power and dosing were not acceptable for samples D and E. In the centrifugation test formulations A, D and E produced precipitation. 

Author Biographies

Eva Maria Xavier Lopes, Faculdades Integradas Aparício Carvalho-FIMCA. Bacharelado em Farmácia. Rua das Ararás, 241-Eldorado, CEP 78912-640. Porto Velho, RO, Brasil.

Acadêmica do curso de Farmácia pelas Faculdades Integradas Aparício Carvalho

Fábio Lopes Moreira de Castilho, Faculdades Integradas Aparício Carvalho-FIMCA. Bacharelado em Farmácia. Rua das Ararás, 241-Eldorado, CEP 78912-640. Porto Velho, RO, Brasil.

Acadêmico do curso de Farmácia pelas Faculdades Integradas Aparício Carvalho

Victória Carolina Freire de Castro, Faculdades Integradas Aparício Carvalho-FIMCA. Bacharelado em Farmácia. Rua das Ararás, 241-Eldorado, CEP 78912-640. Porto Velho, RO, Brasil.

Acadêmica do curso de Farmácia pelas Faculdades Integradas Aparício Carvalho

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Published

2019-10-07

How to Cite

Xavier Lopes, E. M., Moreira de Castilho, F. L., & Freire de Castro, V. C. (2019). QUALITY CONTROL OF 2% KETOCONAZOLE SHAMPOOS IN COMPOUNDING PHARMACIES IN PORTO VELHO, RO, BRAZIL. Infarma - Pharmaceutical Sciences, 31(3), 155–162. https://doi.org/10.14450/2318-9312.v31.e3.a2019.pp155-162

Issue

Vol. 31 No. 3 (2019)

Section

Original article

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