ANTIBACTERIAL POTENTIAL OF THE ESSENTIAL OIL OF LIPPIA ALBA MILL. ASSOCIATED WITH LED LIGHTS

Authors

  • Vitoria Ruana Sales Santos Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405 http://orcid.org/0000-0003-0878-9176
  • Dárcio Luiz de Sousa Júnior Universidade Regional do Cariri, Rua Cel. Antônio Luis, 1161 - 63105-000 - Pimenta - Crato/CE http://orcid.org/0000-0002-1539-9267
  • Jailson de Castro Freitas Centro Universitário Maurício de Nassau, Av. Aguanambi, 251 - José Bonifacio, Fortaleza - CE, 60110-001 http://orcid.org/0000-0001-7223-4365
  • Pedro Everson Alexandre de Aquino Centro Universitário Maurício de Nassau, Av. Aguanambi, 251 - José Bonifacio, Fortaleza - CE, 60110-001 http://orcid.org/0000-0002-4756-081X
  • Maria Karollyna do Nascimento Silva Leandro Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405 http://orcid.org/0000-0002-2215-4110
  • Lívia Maria Garcia Leandro Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405 http://orcid.org/0000-0002-2259-9208
  • Rakel Olinda Macedo da Silva Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405 http://orcid.org/0000-0002-6298-8996

DOI:

https://doi.org/10.14450/2318-9312.v33.e2.a2021.pp188-196

Keywords:

phototherapy, biological products, pharmacological sinergism.

Abstract

Lippia alba, also known as erva cidreira, is an aromatic bush occurring throughout Brazil. Its essential oil has many bioactivities, but few studies of its use are associated to phototherapy. The aim of this study was to evaluate the antibacterial activity of the essential oil of Lippia alba (OEL) associated  with blue, red, and yellow LED (Light Emitting Diode) lights against strains of Staphylococcus aureus and Escherichia coli. The oil was extracted by the  hydrodistillation method. The antibacterial and modulatory activity was performed by the method of gas contact using the oil, LED lights, and  antibiotics. All experiments were carried out in triplicate. The OEL has  antibacterial potential against all strains tested, with a more expressive 
result against the multi-resistant strain of E. coli when associated with the LED lights. The modulation of bacterial resistance, both in the combinations  of oil + antibiotic + LED lights and oil + antibiotics, showed synergism  against the tested multi-resistant strains. Therefore, the essential oil of  Lippia alba associated with LED lights has an antibacterial and modulating  effect by gas contact. These data may contribute to future research linked to  development of new therapeutic strategies to combat resistant microorganisms. 

Author Biographies

Vitoria Ruana Sales Santos, Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405

Biomédica e Pós-graduanda em Citologia Clínica (UNILEÃO)

Dárcio Luiz de Sousa Júnior, Universidade Regional do Cariri, Rua Cel. Antônio Luis, 1161 - 63105-000 - Pimenta - Crato/CE

Biomédico, Especialista em Microbiologia Clínica (Unileão) e Farmacologia Clínica (Urca), Mestre em Química Biológica (Urca)

Jailson de Castro Freitas, Centro Universitário Maurício de Nassau, Av. Aguanambi, 251 - José Bonifacio, Fortaleza - CE, 60110-001

Enfermeiro, Doutor em Ciências da Saúde pela Faculdade de Ciências Médica da Santa Casa de São Paulo.

Pedro Everson Alexandre de Aquino, Centro Universitário Maurício de Nassau, Av. Aguanambi, 251 - José Bonifacio, Fortaleza - CE, 60110-001

Biomédico (UNILEÃO), Mestre e Doutorando em Farmacologia (UFC)

Maria Karollyna do Nascimento Silva Leandro, Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405

Biomédica (UNILEÃO), Mestra em Bioprospecção Molecular (URCA).

Lívia Maria Garcia Leandro, Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405

Biomédica, Especialista em Hematologia Clínica e Microbiologia Clínica (UNILEÃO).

Rakel Olinda Macedo da Silva, Centro Universitário Dr. Leão Sampaio, Av. Maria Letícia Leite Pereira s/n, Lagoa Seca - Cidade Universitária, Juazeiro do Norte - CE, 63040-405

Biomédica (UNILEÃO), Mestra em Bioprospecção Molecular (URCA).

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Published

2021-06-30

How to Cite

Santos, V. R. S., Sousa Júnior, D. L. de, Freitas, J. de C., Aquino, P. E. A. de, Silva Leandro, M. K. do N., Leandro, L. M. G., & Macedo da Silva, R. O. (2021). ANTIBACTERIAL POTENTIAL OF THE ESSENTIAL OIL OF LIPPIA ALBA MILL. ASSOCIATED WITH LED LIGHTS. Infarma - Pharmaceutical Sciences, 33(2), 188–196. https://doi.org/10.14450/2318-9312.v33.e2.a2021.pp188-196

Issue

Vol. 33 No. 2 (2021)

Section

Original article

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