POTENTIAL DRUG INTERACTIONS IN PARTICIPANTS OF A HEALTH EDUCATION PROGRAM, PRESENTING TYPE 2 DIABETIC

Authors

  • Rodrigo Fonseca Lima Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília, DF, Brasil
  • Alexandre Vaz Machado Secretaria de Saúde do Distrito Federal – SES-DF, Hospital Regional de Sobradinho, Área Especial - Q 12 Conjunto D, Sobradinho, DF, Brasil
  • Fernanda Maciel Rebelo Secretaria de Saúde do Distrito Federal – SES-DF, Centro de Saúde nº 01 de Santa Maria, EQ 207/ 307 - Santa Maria Sul, Santa Maria, DF, Brasil
  • Janeth de Oliveira Silva Naves Agência Nacional de Vigilância Sanitária, Setor de Indústria e Abastecimento (SIA) - Trecho 5, Área Especial 57, Brasília, DF, Brasil
  • Tatiana Ramos Lavich Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília, DF, Brasil
  • Jane Dullius Faculdade de Educação, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília, DF, Brasil

DOI:

https://doi.org/10.14450/2318-9312.v27.e3.a2015.pp160-167

Keywords:

pharmacoepidemiology, drug interactions, diabetes mellitus, health education

Abstract

Cross-sectional study in order to determine the prevalence, clinical impact and factors associated with Potential Drug
Interactions (PDI) in participants with type 2 diabetes (DM2) of a health education program. This study involved 71
diabetics grouped according to the presence or absence of PDI and data were obtained individually by a semi-structured
questionnaire. PDI were classified using the UpToDate® database and the participants were compared according to
socio-demographic and clinical variables through chi-square and t student tests. Each participant used 4.6 drugs
on average and over 70% of participants showed some PDI (total of 140 interactions). Over 70% of them required
monitoring of pharmacotherapy and 6.4% of them would need to consider a change in therapy. PDI increased with
the number of drugs prescribed (p<0.001) and did not change according to the gender, age and duration of DM2

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Published

2015-09-30

How to Cite

Lima, R. F., Machado, A. V., Rebelo, F. M., Naves, J. de O. S., Lavich, T. R., & Dullius, J. (2015). POTENTIAL DRUG INTERACTIONS IN PARTICIPANTS OF A HEALTH EDUCATION PROGRAM, PRESENTING TYPE 2 DIABETIC. Infarma - Pharmaceutical Sciences, 27(3), 160–167. https://doi.org/10.14450/2318-9312.v27.e3.a2015.pp160-167

Issue

Vol. 27 No. 3 (2015)

Section

Original article

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