PREVALENCE OF ENTERAL PARASITISM AND ITS ASSOCIATION WITH HEMATOLOGICAL AND BIOCHEMICAL PROFILE IN ADULTS IN CAMETÁ, PARÁ, BRAZIL

Authors

  • Lídia Mendes da Silva Teixeira Faculdade Integrada Brasil Amazônia (FIBRA) Av. Gentil Bittencourt 1144, Nazaré. CEP: 66.040-174. Belém, PA. Brasil.
  • Bárbara Roberta da Costa Loiola Faculdade Integrada Brasil Amazônia (FIBRA) Av. Gentil Bittencourt 1144, Nazaré. CEP: 66.040-174. Belém, PA. Brasil.
  • Enzo Pantoja Lima Laboratório Carlos Lima Rua 13 de Maio, Centro. CEP: 68400-000. Cametá, PA. Brasil
  • Amanda Gabryelle Nunes Cardoso Mello Faculdade Integrada Brasil Amazônia (FIBRA) Av. Gentil Bittencourt 1144, Nazaré. CEP: 66.040-174. Belém, PA. Brasil.

DOI:

https://doi.org/10.14450/2318-9312.v31.e4.a2019.pp293-304

Keywords:

enteral parasitism, hematological profile, biochemistry profile

Abstract

The prevalence of enteral parasitism in adults was analyzed, as well as their hematological and biochemical profiles. It is a prospective, quantitative and cross-sectional study. A total of 76 samples of parasitological, hemogram and biochemical tests from adults between 18 and 65 years old, living in Cametá Couty, Brazil, were collected. At 18 samples (23.68%), no infection by parasites was detected, while 58 (76.31%) showed infection by helminths and/or protozoa. The affected samples presented a slight decrease in the levels of hemoglobin, hematocrit, MCV, HCM, while an increase of leucocytes and segmented cells was observed. However, statistically, such result was not significant when related to the parasite presence. Concerning the biochemical parameters, there were no significant differences between the control group (n = 18) and the positive participants (n = 58), although a significant increase in triglyceride, total cholesterol, and LDL (p<0.0001) levels of positive versus negative subjects may be noted. Among 58 positive samples, 40 were infected by one, and 18 by two or more parasites. Regardless of the number of parasites, only biochemical changes were observed, suggesting that the parasite uses plasma lipoproteins from the infected organism as lipid carriers, to promote an acute phase response.

Author Biographies

Lídia Mendes da Silva Teixeira, Faculdade Integrada Brasil Amazônia (FIBRA) Av. Gentil Bittencourt 1144, Nazaré. CEP: 66.040-174. Belém, PA. Brasil.

Graduada em Farmácia

Bárbara Roberta da Costa Loiola, Faculdade Integrada Brasil Amazônia (FIBRA) Av. Gentil Bittencourt 1144, Nazaré. CEP: 66.040-174. Belém, PA. Brasil.

Graduada em Farmácia

Enzo Pantoja Lima, Laboratório Carlos Lima Rua 13 de Maio, Centro. CEP: 68400-000. Cametá, PA. Brasil

Graduado em Farmácia

Amanda Gabryelle Nunes Cardoso Mello, Faculdade Integrada Brasil Amazônia (FIBRA) Av. Gentil Bittencourt 1144, Nazaré. CEP: 66.040-174. Belém, PA. Brasil.

Graduada em Ciências Farmacêuticas e pós­-graduada em Doenças Tropicais pela Universidade Federal do Pará (UFPA), com titulo de Mestre em Patologia das Doenças Tropicais. Desenvolveu a dissertação no Laboratório de Toxicologia da UFPA sob título "Marcadores de estresse oxidativo em pacientes com malária por Plasmodium vivax, durante o tratamento com Primaquina e Cloroquina". Além disso, possui experiência na área de Genética com ênfase em Biotecnologia e Biologia Molecular de Micr­organismos, sobre a abordagem metagenoma do lago da Usina Hidrelétrica de Tucuruí (PA). Desenvolveu doutoramento em Rede de Inovação Farmacêutica pela UFPA sob o título da tese "ATIVIDADE DA ENZIMA CITOCROMO­P450 2D6 E PRIMAQUINA EM PACIENTES INFECTADOS POR Plasmodium vivax, NO ESTADO DO PARÁ, BRASIL". Atualmente, é docente da Faculdade Brasil Amazônia (FIBRA), Faculdade Pan-Amazônica (FAPAN) e Escola Superior da Amazônia (ESAMAZ). 

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Published

2019-12-31

How to Cite

Teixeira, L. M. da S., Loiola, B. R. da C., Lima, E. P., & Mello, A. G. N. C. (2019). PREVALENCE OF ENTERAL PARASITISM AND ITS ASSOCIATION WITH HEMATOLOGICAL AND BIOCHEMICAL PROFILE IN ADULTS IN CAMETÁ, PARÁ, BRAZIL. Infarma - Pharmaceutical Sciences, 31(4), 293–304. https://doi.org/10.14450/2318-9312.v31.e4.a2019.pp293-304

Issue

Vol. 31 No. 4 (2019)

Section

Original article

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