DRUG-DRUG INTERACTION IN ELDERLY PATIENTS WITH DYSLIPIDEMIA DESEASE IN A BASIC HEALTH UNITY IN SANTANA OF CARIRI, CE, BRAZIL

Authors

  • Lucilene Galdino de Barros Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360
  • Felisberto Farias Santos Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360
  • Dárcio Luiz de Sousa Júnior Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360 http://orcid.org/0000-0002-1539-9267
  • Ana Emília Formiga Marques Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360 http://orcid.org/0000-0003-1568-7231

DOI:

https://doi.org/10.14450/2318-9312.v32.e2.a2020.pp137-143

Keywords:

drug-drug interaction, pharmaceutical care, dyslipidemia

Abstract

This study aimed to perform an analysis of drug interactions based on data from medical prescriptions for elderly patients using drugs for dyslipidemia in a basic health unit in the city of Santana do Cariri, CE.
Data collection and analysis were carried out between August and September 2018. This is a descriptive, quantitative, retrospective, and cross-sectional study. Micromedex® platform was used to identify possible drug interactions. Elderly patients with some dyslipidemia, with a minimum age of 60 and a maximum of 89 years, were selected. A total sample of 40 prescriptions was obtained, where the population was 103 prescriptions, in which 80% were female and 20% male. A total of 37 interactions was identifi ed; among them, the drug simvastatin was more frequently interacting with other drugs, the most frequent was amlodipine. These two drugs interaction is considered serious, due to the risk of myopathies and rhabdomyolysis. In view of these results, the importance of implementing a clinical pharmacy service is observed, in order to identify possible problems related to drug-drug interactions, improving the patient pharmacotherapy and quality of life, as well as minimizing the risks for their health.

Author Biographies

Lucilene Galdino de Barros, Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360

Farmacêutica pela Faculdade de Medicina Estácio de Juazeiro do Norte

Felisberto Farias Santos, Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360

Farmacêutico pela Faculdade de Medicina Estácio de Juazeiro do Norte, Pós-graduando em Faarmacologia Clínica (Urca).

Dárcio Luiz de Sousa Júnior, Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360

Biomédico, Especialista em Microbiologia Clínica (Unileão) e Farmacologia Clínica (Urca), Mestrando em Química Biológica (Urca)

Ana Emília Formiga Marques, Faculdade de Medicina Estácio de Juazeiro do Norte, Avenida, R. Ten. Raimundo Rocha, 515 - Cidade Universitária, Juazeiro do Norte - CE, 63040-360

Farmacêutica, Mestre em Ciências Naturais e Biotecnologia, Docente da Faculdade de Medicina Estácio de Juazeiro do Norte

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Published

2020-07-07

How to Cite

Barros, L. G. de, Santos, F. F., Sousa Júnior, D. L. de, & Marques, A. E. F. (2020). DRUG-DRUG INTERACTION IN ELDERLY PATIENTS WITH DYSLIPIDEMIA DESEASE IN A BASIC HEALTH UNITY IN SANTANA OF CARIRI, CE, BRAZIL. Infarma - Pharmaceutical Sciences, 32(2), 137–143. https://doi.org/10.14450/2318-9312.v32.e2.a2020.pp137-143

Issue

Vol. 32 No. 2 (2020)

Section

Original article

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