HYPODERMOCLYSIS IN ONCOLOGICAL PALLIATIVE CARE: SYSTEMATIC REVIEW

Authors

DOI:

https://doi.org/10.14450/2318-9312.v37.e1.a2025.pp15-22

Keywords:

hypodermoclysis, palliative care, comfort in finitude, fragile venous access, oncology patient.

Abstract

Objective: This article addresses the treatment of cancer patients, referring to venous fragility induced by cancer treatment, highlighting hypodermoclysis as a therapeutic alternative to provide patient comfort, especially in cases of finitude. Subcutaneous hypodermoclysis stands out as a less invasive, safe and less expensive method for administering substances. However, there is a preference for the intravenous route in clinical practice. Hypodermoclysis has a lower incidence of complications compared to peripheral venipuncture. Therefore, greater dissemination of this knowledge and adopting hypodermoclysis in cancer patients is advisable. Methodology: A systematic review was carried out according to the PRISMA flowchart. Scientific articles were obtained through a search in periodicals published between the years 2012 and 2022 in the databases Scientific Electronic Library Online (Scielo), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) and the National Library of Medicine (Pubmed/Medline) using “hypodermoclysis” AND “palliative care” as keywords. Results: Six studies were analyzed, and suggest indications, contraindications, advantages and disadvantages related to subcutaneous use; comparison between peripheral venous access and hypodermoclysis techniques; administration sites; subcutaneous route prescription by professionals, interprofessional action and the pivotal role of pharmacists related to hypodermoclysis. Conclusion: This is a safe and effective alternative for administering medications, especially in patients with venous fragility, but many professionals neglect it. The pharmacist's role is not just important but essential in promoting hypodermoclysis inclusion and leading initiatives for its understanding and applicability.

Author Biographies

Jakson Gustavo Haverroth, Fundação Educacional de Brusque (UNIFEBE - SC). Rua Vendelino Maffezzolli 333 - Santa Terezinha, Brusque (SC). CEP 88352-360.

Farmacêutico de Suprimento Hospitalar no Centro Hospitalar Unimed de Blumenau (SC). Pós-graduando em Farmácia Hospitalar pela Fundação Educacional de Brusque no Hospital Santa Catarina de Blumenau (SC). Farmacêutico responsável técnico por e gestor de Farmácia de Dispensação Comunitária Privada (10 anos) no município de Blumenau.

Eduardo Manoel Pereira, Universidade da Região de Joinville - Rua Paulo Malschitski, 10 - Zona Industrial Norte, Joinville (SC). CEP 89219-710.

Farmacêutico-Bioquímico (Universidade Federal de Alfenas - UNIFAL) há 20 anos e professor Mestre em Farmacologia (Universidade Federal do Paraná) há 15 anos em cursos de gradução e pós-gradução em farmácia, medicina, ondotologia e psicologia na Universidade da Região de Joinville e na Fundação Educacional de Brusque (UNIFEBE). Pesquisador nas áreas pré-clínica (modelos animais de dor, diabetes, gastrite, estresse oxidativo) e clínica (acompanhamento farmacoterapêutico, farmácia clínica, avaliação de erros de prescrição, interações medicamentosas, revisões sistemáticas).

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Published

2026-03-31

How to Cite

Haverroth, J. G., & Pereira, E. M. (2026). HYPODERMOCLYSIS IN ONCOLOGICAL PALLIATIVE CARE: SYSTEMATIC REVIEW. Infarma - Pharmaceutical Sciences, 37(1), 15–22. https://doi.org/10.14450/2318-9312.v37.e1.a2025.pp15-22

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Section

Review Article

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