Evaluation of Caffeine in Drug Associations

Authors

  • Débora Mendes Lopes Faculdade de Saúde Ibituruna – FASI, Montes Claros-MG, Brasil
  • João Lúcio Cardoso Faculdade de Saúde Ibituruna – FASI, Montes Claros-MG, Brasil
  • Ronilson Ferreira Freitas Faculdades Integradas Pitágoras de Montes Claros – FIPMoc, Montes Claros-MG, Brasil
  • Vanessa de Andrade Royo Faculdade de Saúde Ibituruna – FASI, Montes Claros-MG, Brasil. Faculdades Integradas Pitágoras de Montes Claros – FIPMoc, Montes Claros-MG, Brasil. 3Universidade Estadual de Montes Claros – UNIMONTES, Montes Claros-MG, Brasil

DOI:

https://doi.org/10.14450/2318-9312.v25.e2.a2013.pp71-75

Keywords:

Caffeine, drug association, consumption, dose

Abstract

Caffeine is a natural methylxanthine consumed worldwide in foods and in combination therapy, but, according to the literature, some of its effects and mechanism of action are not well defined. The objective of this study was to evaluate the benefits and risks related to the association of caffeine in medicines, as well as making comparison of doses cited in the literature with those found in more commercialized medicines and foods consumed by population in diary basis. A survey of thirty-five medicines most associated with caffeine sold in a comercial pharmacy of dispensing was done. It was noted that caffeine usually is associated with three classes of medicines most frequently used by the population classified pharmacologically as analgesic, anti-inflammatory and muscle relaxants. Besides, 69% of dispensed medicines was associated with spontaneous search by patients, 91% of such medicines presented caffeine sub-therapeutic doses (as literature refers) and in 75% of cases caffeine amount was less than 50 mg, similar to dose of food consumed per person/day. Thus, it is concluded that the use of caffeine in drugs still requires scientific evidence concerning its benefits and studies to define better criteria for caffeine therapeutic use.

Downloads

Published

2013-08-08

How to Cite

Lopes, D. M., Cardoso, J. L., Freitas, R. F., & Royo, V. de A. (2013). Evaluation of Caffeine in Drug Associations. Infarma - Pharmaceutical Sciences, 25(2), 71–75. https://doi.org/10.14450/2318-9312.v25.e2.a2013.pp71-75

Issue

Vol. 25 No. 2 (2013)

Section

Original article

License

Authors who publish in this journal agree to the following terms:

 

  1. Authors retain the copyright and grant the journal the right of first publication, with the work simultaneously licensed under the Licença Creative Commons Attribution which allows the sharing of work with acknowledgment of authorship and initial publication in this journal.
  2. Authors are authorized to take additional contracts separately, for non-exclusive distribution of the version of the work published in this journal (e.g. publish in institutional repository or as a book chapter), with acknowledgment of authorship and initial publication in this journal.
  3. Authors are allowed and encouraged to publish and distribute their work online (e.g. in institutional repositories or on their personal page) at any point before or during the editorial process, as this can generate productive changes as well as increase the impact and Citation of published work (See O Efeito do Acesso Livre ).