ANTIMICROBIAL AND ANTIVIRAL AGENTS WITH POTENTIAL THERAPEUTIC USE FOR COVID-19

Authors

  • Hellen Cryslen Bernardo Bezerra Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará
  • Daniel Parente Xavier Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará
  • Tatiana Paschoalette Rodrigues Bachur Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará
  • Gislei Frota Aragão Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará

DOI:

https://doi.org/10.14450/2318-9312.v32.e2.a2020.pp109-119

Keywords:

Coronavirus infections, Drug therapy, Anti-infective agents

Abstract

The disease caused by the new SARS-CoV-2 coronavirus, called COVID-19, has already infected more than 6.5 million people worldwide. To date, there is no proven eff ective treatment against the virus, but some drugs already used in other diseases have shown eff ectiveness in vitro or even in humans, such as some antimicrobial agents. The objective of this bibliographic research was to provide an overview of the published evidence, up to the research date, about experimental studies and clinical trials that used antimicrobial drugs as a treatment proposal for the disease by the new coronavirus. 75 articles from journals indexed in the MEDLINE database were included. The results showed that the drugs Lopinavir/Ritonavir, chloroquine and hydroxychloroquine demonstrated to act in the clinical improvement of patients diagnosed with COVID-19. However, more evidence is needed to confi rm the data currently available.

Author Biographies

Hellen Cryslen Bernardo Bezerra, Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará

Acadêmica do curso de Medicina da Universidade Estadual do Ceará.

Daniel Parente Xavier, Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará

Acadêmico do curso de Medicina da Universidade Estadual do Ceará.

Tatiana Paschoalette Rodrigues Bachur, Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará

Docente do curso de Medicina da Universidade Estadual do Ceará.

Gislei Frota Aragão, Universidade Estadual do Ceará - CCS - Curso de Medicina Av. Dr. Silas Munguba, 1700 Itaperi CEP: 60.714-903 Fortaleza - Ceará

Docente do curso de Medicina da Universidade Estadual do Ceará.

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Published

2020-07-07

How to Cite

Bezerra, H. C. B., Xavier, D. P., Bachur, T. P. R., & Aragão, G. F. (2020). ANTIMICROBIAL AND ANTIVIRAL AGENTS WITH POTENTIAL THERAPEUTIC USE FOR COVID-19. Infarma - Pharmaceutical Sciences, 32(2), 109–119. https://doi.org/10.14450/2318-9312.v32.e2.a2020.pp109-119

Issue

Vol. 32 No. 2 (2020)

Section

Review Article

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