Pharmacotherapy Study of Pain In Post-surgical Patients at Hospital de Clínicas of the Federal University of Paraná

Abstract

Post-operatory pain is an acute pain difficult to effectively control. The object of this study was to assess, as compared to what is found in international literature, the incidence of post-operatory pain in patients submitted to digestive tract surgery, managed with standard analgesic and anti-inflammatory drugs at Hospital de Clínicas, the university hospital of the Federal University of Paraná, UFPR. One hundred patients of both genders, age group between 19 and 65 years, were followed from the Immediate Post-Anesthetic Recovery Unit until discharge, or up to 72 hours after surgery, through a double blind study consisting of oral questions about pain feeling and intensity. We compared the pain rate in patients who were given dypirone and dypirone plus ketoprofen, or dypirone plus tramadol, or dypirone plus ketoprofen and tramadol at given times. Of the 91 patients examined at the Immediate Post-Anesthetic Recovery Unit, 33 reported pain. Among the 93 patients followed since their return to the admission unit until the first drug administration on the following day, 30 reported pain. On day one post-op, 93 patients were followed of which 24 reported pain. On day two, of 37 patients, 11 still had pain. There was no statistically significant difference among patients who were given dypirone alone or associated with other drugs. This study showed that the incidence of acute continuous post-op pain in patients at Hospital de Clínicas of the UFPR managed with standard analgesic and antiinflammatory drugs was thirty percent, the minimal margin shown in international literature.